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| Anaerobic Fermentation of Synthesis Gas for Organic Acids and Alcohols Production |
1.Key Laboratory of Renewable Energy and Gas Hydrate, Guangzhou Institute of Energy Conversion, Chinese Academy of Sciences, Guangzhou 510640, China
2.Graduate School of Chinese Academy of Sciences，Beijing 100039，China |
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Abstract Gasification of coal, oil, biomass or organic wastes generates synthesis gas, which consists primarily of CO, H2 and CO2. Synthesis gas may be used as substrates by some anaerobic bacteria to produce liquid fuels and chemicals such as ethanol, acetic acid, butanol and butyric acid. Anaerobic fermentation of synthesis gas is considered a promising and competing technology due to its advantages over catalytic techniques, and it's expected that synthesis gas fermentation will play a role in the conversion of biomass and organic wastes. Research progress in production of organic acids and alcohols via synthesis gas fermentation was reviewed, focusing on microorganisms, the metabolic pathway, key enzymes (especially carbon monoxide dehydrogenase /acetyl-CoA synthase) and bioreactors. Suggestions were also given to indicate areas where advances can be made.
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Received: 05 November 2009
Published: 25 March 2010
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| ［1］ Phillips J R, Klasson K T, Clausen E C, et al. Biological production of ethanol from coal synthesis gas. Applied Biochemistry and Biotechnology. 1993, 3940(1): 559571.
［2］ Maschio G, Lucchesi A, Stoppato G. Production of syngas from biomass. Bioresource Technology. 1994, 48(2):119126.
［3］ Ragauskas A J, Williams C K, Davison B H, et al. The path forward for biofuels and biomaterials. Science. 2006, 311: 484489.
［4］ Huber G W, Iborra S, Corma A. Synthesis of transportation fuels from biomass: chemistry, catalysts, and engineering. Chemical Reviews. 2006, 106:40444098.
［5］ Van Kasteren J M N. Cogasification of wood and polyethylene with the aim of CO and H2 production. Journal of Material Cycles and Waste Management. 2006, 8:9598.
［6］ Henstra A M, Sipma J, Rinzema A, et al. Microbiology of synthesis gas fermentation for biofuel production. Current Opinion in Biotechnology. 2007, 18:200206.
［7］ Fontaine F E, Peterson W H, McCoy E, et al. A new type of glucose fermentation by Clostridium thermoaceticum. Journal of Bacteriology. 1942, 43(6): 701715.
［8］ Collins M D, Lawson P A, Willems A, et al. The phylogeny of the genus Clostridium: proposal of five new genera and eleven new species combinations. International Journal of Systematic Bacteriology. 1994, 44:812826.
［9］ Kerby R, Zeikus J G. Growth of Clostridium thermoacetium on H2/CO2 or CO as energy source. Current Microbiology. 1983, 8:2730.
［10］ Wood H G. A study of carbon dioxide fixation by mass determination of the types of C13acetate. The Journal of Biological Chemistry. 1952, 194: 905931.
［11］ Ljungdahl L G, Andreesen J R. Tungsten, a component of active formate dehydrogenase from Clostridium thermoaceticum. FEBS Letters. 1975, 54: 279282.
［12］ Ljungdahl L, Irion E, Wood H G. Role of corrinoids in the total synthesis of acetate from CO2 by Clostridium thermoaceticum. Federation Proceedings. 1966, 25: 16421648.
［13］ Drake H L, Hu S I, Wood H G. Purification of five components from Clostridium thermoaceticum which catalyze synthesis of acetate from pyruvate and methyltetrahydrofolate. Properties of phosphotransacetylase. The Journal of Biological Chemistry. 1981, 256: 1113711144.
［14］ Ragsdale S W, Wood H G. Acetate biosynthesis by acetogenic bacteria. Evidence that carbon monoxide dehydrogenase is the condensing enzyme that catalyzes the final steps of the synthesis. The Journal of Biological Chemistry. 1985, 260: 39703977.
［15］ Ljungdahl L G. The autotrophic pathway of acetate synthesis in acetogenic bacteria. Annual Review of Microbiology. 1986, 40: 415450.
［16］ Worden R M, Grethlein A J, Zeikus J G, et al. Butyrate production from carbon monoxide by Butyribacterium methylotrophicum. Applied Biochemistry and Biotechnology. 1989, 20/21: 687698 .
［17］ Grethlein A J, Worden R M, Jain M K, et al. Continuous production of mixed alcohols and acids from carbon monoxide. Applied Biochemistry and Biotechnology. 1990, 24/25:875884.
［18］ Grethlein A J, Worden R M, Jain M K, et al. Evidence for production of nbutanol from carbon monoxide by Butyribacterium methylotrophicum. Journal of Fermentation and Bioengineering. 1991, 72(1):5860.
［19］ Tanner R S, Miller L M, Yang D. Clostridium ljungdahlii sp. nov., an acetogenic species in clostridial rRNA homology groupI. International Journal of Systematic Bacteriology. 1993, 43(2): 232236.
［20］ Barik S, Prieto S, Harrison S B, et al. Biological production of alchohols from coal through indirect liquifcation. Applied Biochemistry and Biotechnology. 1988, 28:363378.
［21］ Gaddy J L, Clausen E C. Clostridium ljungdahlii, an anaerobic ethanol and acetate producing microorganism:U.S., 612221, 1992.
［22］ Klasson K T, Ackerson M D, Clausen E C, et al. Biological conversion of coal and coalderived synthesis gas. Fuel,1993, 72 (12):16731678.
［23］ Klasson K T, Ackerson M D, Clausen E C, et al. Bioconversion of synthesis gas into liquid or gaseous fuels. Enzyme Microbial Technology. 1992, 14: 602608.
［24］ Liou J S C，Balkwill D L，Drake G R，et al．Clostridium carboxidivorans sp. nov., a solventproducing clostridium isolated from an agricultural settling lagoon, and reclassification of the acetogen Clostridium scatologenes strain SL1 as Clostridium drakei sp. nov. . International Journal of Systematic and Evolutionary Microbiology. 2005, (55):20852091.
［25］ Rajagopalan S, Datar R P, Lewis R S. Formation of ethanol from carbon monoxide via a new microbial catalyst. Biomass and Bioenergy. 2002, 23: 487493.
［26］ Datar R P, Shenkman R M, Cateni B G, et al. Fermentation of biomassgenerated producer gas to ethanol. Biotechnology and Bioengineering. 2004, 86 (5): 587594.
［27］ Abrini J, Naveau H, Nyns E. Clostridium autoethanogenum sp. nov., an anaerobic bacterium that produces ethanol from carbon monoxide. Archives of Microbiology. 1994, 161:345351.
［28］ Wood H G, Ljungdahl L G. Autotrophic character of acetogenic bacteria. In Variations in Autotrophic Life. Shively J M, Barton L L, Eds. SanDiego, CA: Academic Press. 1991, 201250 .
［29］ Drake H L, G?ssner A S, Daniel S L. Old acetogens, new light. Annals of the New York Academy of Sciences. 2008, 1125: 100128.
［30］ Grethlein A J, Jain M K, 1992. Bioprocessing of coalderived synthesis gas by anaerobic bacteria. Trends in Biotechnology, 10: 418423.
［31］ Diekert G B, Thauer R K. Carbon monoxide oxidation by Clostridium thermoaceticum and Clostridium formicoaceticum. Journal of Bacteriology. 1978, 136:597606.
［32］ Ragsdale S W, Clark J E, Ljungdahl L G, et al. Properties of purified carbon monoxide dehydrogenase from Clostridium thermoaceticum a nickel, ironsulfur protein. The Journal of Biological Chemistry. 1983, 258:23642369.
［33］ Diekert G, Ritter M. Purification of the nickel protein carbon monoxide dehydrogenase of Clostridium thermoaceticum. FEBS Letters. 1983, 151:4144.
［34］ Xia J, Sinclair J F, Baldwin T O, et al. Carbon monoxide dehydrogenase from Clostridium thermoaceticum: quaternary structure, stoichiometry of its SDSinduced dissociation, and characterization of the fastermigrating form. Biochemistry. 1996, 35(6):19651971.
［35］ Ragsdale S W. Life with carbon monoxide. Critical Reviews in Biochemistry and Molecular Biology. 2004, 39:165195 .
［36］ Tan X S, Bramlett M R, Lindahl P A. Effect of Zn on acetyl coenzyme a synthase: evidence for a conformational change in the a subunit during catalysis. Journal of the American Chemical Society. 2004, 126(19): 59545955.
［37］ Bramlett M R, Tan X S, Lindahl P A. Inactivation of acetylCoA synthase/carbon monoxide dehydrogenase by copper. Journal of the American Chemical Society. 2003, 125(31): 93169317.
［38］ Maynard E L, Lindahl P A. Evidence of a molecular tunnel connecting the active sites for CO2 reduction and acetylCoA synthesis in acetylCoA synthase from Clostridium thermoaceticum. Journal of the American Chemical Society. 1999, 121:92219222.
［39］ Seravalli J, Ragsdale S W. Channeling of carbon monoxide during anaerobic carbon dioxide fixation. Biochemistry. 2000, 39(6):12741277.
［40］ Bredwell M D, Srivastava P, Worden R M. Reactor design issues for synthesisgas fermentations. Biotechnology Progress. 1999, 15(5): 834844.
［41］ Alonso C, Suidan M T, Sorial G A, et al. Gas treatment in tricklebed biofilters: biomass, how much is enough? . Biotechnology and Bioengineering. 1997, 54: 583594.
［42］ Bredwell M D, Worden R M. Masstransfer properties of microbubbles: Experimental studies. Biotechnology Progress. 1998, 14 (1): 3138.
［43］ Sebba F. Foams and Biliquid Foams Aphrons. Wiley: New York, 1987.
［44］ Kaster J A, Michelsen D L, Velander W H. Increased oxygen transfer in a yeast fermentation using a microbubble dispersion. Applied Biochemistry and Biotechnology. 1990, 24/25:469484.
［45］ Klasson K T, Ackerson M D, Clausen E C, et al. Bioreactors for synthesis gas fermentations. Resources, Conservation and Recycling. 1991, 5: 145165. |
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