中国生物工程杂志

Hair follicle stem cells located bulge region of hair follicle, had characteristics of all adult stem cells, including slow-cycling, undifferentiated. They also had the abilities of self-renew and proliferation in vitro. CD34、K15、K19 and Nestin might be the makers of the hair follicle stem cells. They could be induced to differentiate to neurons, glial cells, keratinocytes, smooth muscle cells ,melanocytes In vitro and neurons, melanocytes in vivo. There were many signals in regulating the hair follicle stem cells involved Wnt signal、BMP signal and NFATc1etc.