Advances in Application of Silk Fibroin/Chitosan Composite in Tissue Engineering

doi:10.13523/j.cb.20171015

China Biotechnology

2017, Vol. 37

Issue (10): 111-117 DOI: 10.13523/j.cb.20171015

Advances in Application of Silk Fibroin/Chitosan Composite in Tissue Engineering

LI Da-wei, HE Jin, HE Feng-li, LIU Ya-li, DENG Xu-dong, YE Ya-jing, YIN Da-chuan

Key Laboratory for Space Bioscience and Biotechnology, School of Life Science, Northwestern Polytechnical University, Xi'an 710072, China

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Abstract Silk fibroin (SF) and chitosan (CS) have excellent biocompatibility and biodegradability, however the disadvantages of pure SF and CS scaffold limit their application in tissue engineering. SF/CS composites that can overcome the shortcoming of pure SF and CS scaffold have excellent mechanical properties, plasticity, tunable porosity and pore size, and component complementary advantages. SF/CS composites (micro/nano particles, membranes, nanofibers, hydrogels and 3D porous scaffolds) have been used in bone, cartilage, skin, nerve, fat, heart and cornea tissue engineering and injury repair. At present, the research on SF/CS composites at home and abroad is still in its infancy. The characteristics, the preparation methods and application of SF/CS composites in tissue engineering were briefly introduced.

Key words： Silk fibroin Chitosan Tissue engineering scaffold Tissue engineering

Received: 27 June 2017 Published: 25 October 2017

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	HE Feng-li
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	DENG Xu-dong

Cite this article:

LI Da-wei, HE Jin, HE Feng-li, LIU Ya-li, DENG Xu-dong, YE Ya-jing, YIN Da-chuan. Advances in Application of Silk Fibroin/Chitosan Composite in Tissue Engineering. China Biotechnology, 2017, 37(10): 111-117.

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https://manu60.magtech.com.cn/biotech/10.13523/j.cb.20171015 OR https://manu60.magtech.com.cn/biotech/Y2017/V37/I10/111


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