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中国生物工程杂志

China Biotechnology
China Biotechnology
China Biotechnology  2015, Vol. 35 Issue (9): 114-121    DOI: 10.13523/j.cb.20150916
    
Research Advances in Molecular Biology of Pseudomonas Lipases
ZHA Dai-ming1,2, ZHANG Bing-huo1, LI Han-quan1, YAN Yun-jun2
1 School of Pharmacy and Life Sciences, Jiujiang University, Jiujiang 332000, China;
2 College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China
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Abstract  

Microbial lipases, being major sources of commercial ones, which have been widely utilized in many industrial fields, such as foods, beverages, lipids, detergents, feeds, textiles, leathers, advanced materials, fine chemicals, medicines, cosmetics, papermaking, pollution treatment, and bioenergy, etc. Compared with other microbial lipases, bacterial lipases have more types of reactions and exhibit higher activity and better stability in many reactions. Amongst bacterial lipases, the most excellent ones are those being from the genus Pseudomonas. As one of the most excellent and the most widely used lipases, the study on Pseudomonas lipases has been a hot topic in the field of lipases. Research advances in molecular biology of Pseudomonas lipases, including mining and cloning of genetic resources, molecular mechanisms of gene expression regulation and protein secretion, strategies for efficient overexpression, protein crystallization and 3D structure analysis, and protein engineering, were summarized and reviewed. Furthermore, the future research directions of Pseudomonas lipases were prospected so as to provide a useful reference for the follow-up studies.

Key words： Pseudomonas      Lipase      Gene expression and regulation     
Received: 22 April 2015      Published: 25 September 2015
ZTFLH:  Q814.9  
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Cite this article:

ZHA Dai-ming, ZHANG Bing-huo, LI Han-quan, YAN Yun-jun. Research Advances in Molecular Biology of Pseudomonas Lipases. China Biotechnology, 2015, 35(9): 114-121.

URL:

https://manu60.magtech.com.cn/biotech/10.13523/j.cb.20150916     OR     https://manu60.magtech.com.cn/biotech/Y2015/V35/I9/114


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