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中国生物工程杂志

China Biotechnology
China Biotechnology  2015, Vol. 35 Issue (6): 68-74    DOI: 10.13523/j.cb.20150611
    
Research Progress of Agarose in Tissue Engineering
LUO Si-shi1, TANG Shun-qing2
1. Guangzhou Trauer Biotechnology CO., Ltd, Guangzhou 510663, China;
2. College of Life Sciences and Biotechnology, Jinan University, Guangzhou 510600, China
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Abstract  

Agarose, which is resourceful and low-cost, is one of the natural high polymer materials with biosecurity and biodegradability. It can be made into gel with three-dimensional network structure and plastic shape. Comparing with other natural materials, agarose have advantages in mechanical properties, such as tensile strength, resistance to compression, viscoelasticity, rheological property and so on. On account of the property of anti-adhesion, agarose tissue engineering scaffold, which is for filling, repairing or regenerating defective tissue, must be composited with other materials or custom-made in suitable ways, in order to enhance its histocompatibility. Research progresses have been made in tissue engineering, although the research history of agarose is not so long. The properties of microstructure and mechanics make it a suitable material for tissue engineering of cartilage, nerve, bone, cornea, oral mucosa, especially in the field of cartilage. So far, there is a long distance between research and clinical usage, and scaffold preparation and mechanism study may be the research hotspots of agarose in the future.



Key wordsAgarose      Tissue engineering      Cytocompatibility      Biodegradability      Gelation ability     
Received: 27 February 2015      Published: 25 June 2015
ZTFLH:  R-1  
Cite this article:

LUO Si-shi, TANG Shun-qing. Research Progress of Agarose in Tissue Engineering. China Biotechnology, 2015, 35(6): 68-74.

URL:

https://manu60.magtech.com.cn/biotech/10.13523/j.cb.20150611     OR     https://manu60.magtech.com.cn/biotech/Y2015/V35/I6/68


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