[1] King A M, Adams M J, Carstens E B, et al.Virus taxonomy: classification and nomenclature of viruses: Ninth Report of the International Committee on Taxonomy of Viruses. San Diego, CA: Elsevier Academic Press, 2012.
[2] Zaki A M, van Boheemen S, Bestebroer T M, et al. Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia. N Engl J Med, 2012, 367(19): 1814-1820.
[3] Enjuanes L, Almazán F, Sola I, et al. Biochemical aspects of coronavirus replication and virus-host interaction. Annu Rev Microbiol, 2006, 60: 211-230.
[4] Masters PS. The molecular biology of coronaviruses. Adv Virus Res, 2006, 48(6): 193-292.
[5] Fu K, Baric R S. Map locations of mouse hepatitis virus temperature-sensitive mutants: confirmation of variable rates of recombination. J Virol, 1994, 68(11): 7458-7466.
[6] Masters PS. Reverse genetics of the largest RNA viruses. Adv Virus Res, 1999, 53: 245-264.
[7] Baric R S, Fu K S, Schaad M C, et al. Establishing a genetic recombination map for MHV-A59 complementation groups. Virology, 1990, 177(2): 646-656.
[8] Kusters J G, Jager E J, Niesters H G, et al. Sequence evidence for RNA recombination in field isolates of avian coronavirus infectious bronchitis virus. Vaccine, 1990, 8(6): 605-608.
[9] Makino S, Keck J G, Stohlman S A, et al. High-frequency RNA recombination of murine coronaviruses. J Virol, 1986, 57(3): 729-737.
[10] Almazán F, Gonzalez J M, Penzes Z, et al. Engineering the largest RNA virus genome as an infectious bacterial artificial chromosome. Proc Natl Acad Sci USA, 2000, 97(10): 5516-5521.
[11] Almazán F, DeDiego M L, Galan C, et al. Construction of a SARS-CoV infectious cDNA clone and a replicon to study coronavirus RNA synthesis. J Virol, 2006, 80(21): 10900-10906.
[12] St-Jean J R, Desforges M, Almazán F, et al. Recovery of a neurovirulent human coronavirus OC43 from an infectious cDNA clone. J Virol, 2006, 80(7): 3670-3674.
[13] Balint A, Farsang A, Zadori Z, et al. Molecular characterization of feline infectious peritonitis virus Strain DF-2 and studies of the role of ORF3 abc in viral cell tropism. J Virol, 2012, 86(11): 6258-6267.
[14] Almazán F, DeDiego M L, Sola I, et al. Engineering a replication-competent, propagation-defective Middle East respiratory syndrome coronavirus as a vaccine candidate. mBio, 2013, 4(5): e00650-13.
[15] Pfefferle S, Krahling V, Ditt V, et al. Reverse genetic characterization of the natural genomic deletion in SARS-coronavirus strain Frankfurt-1 open reading frame 7b reveals an attenuating function of the 7b protein in vitro and in vivo. Virol J, 2009, 6: 131.
[16] Yount B, Curtis K M, Baric R S. Strategy for systematic assembly of large RNA and DNA genomes: transmissible gastroenteritis virus model. J Virol, 2000, 74(22): 10600-10611.
[17] Becker M M, Graham R L, Donaldson E F, et al. Synthetic recombinant bat SARS-like coronavirus is infectious in cultured cells and in mice. Proc Natl Acad Sci USA, 2008, 105(50): 19944-19949.
[18] Scobey T, Yount B L, Sims A C, et al. Reverse genetics with a full-length infectious cDNA of the Middle East respiratory syndrome coronavirus. Proc Natl Acad Sci USA, 2013, 110(40): 16157-16162.
[19] Yount B, Denison M R, Weiss S R, et al. Systematic assembly of a full-length infectious cDNA of mouse hepatitis virus strain A59. J Virol, 2002, 76(21): 11065-11078.
[20] Fang S, Chen B, Tay F P, et al. An arginine-to-proline mutationin a domain with undefined functions within the helicase protein (Nsp13) is lethal to the coronavirus infectious bronchitis virus in cultured cells. Virology, 2007, 358(1): 136-147.
[21] Tan Y W, Fang S, Fan H, et al. Amino acid residues critical for RNA-binding in the N-terminal domain of the nucleocapsid protein are essential determinants for the infectivity of coronavirus in cultured cells. Nucleic Acids Res, 2006, 34(17): 4816-4825.
[22] Donaldson E F, Yount B, Sims A C, et al. Systematic assembly of a full-length infectious clone of human coronavirus NL63. J Virol, 2008, 82(23): 11948-11957.
[23] Thiel V, Herold J, Schelle B, et al. Infectious RNA transcribed in vitro from a cDNA copy of the human coronavirus genome cloned in vaccinia virus. J Gen Virol, 2001, 82(6): 1273-1281.
[24] Casais R, Thiel V, Siddell S G, et al. Reverse genetics system for the avian coronavirus infectious bronchitis virus. J Virol, 2001, 75(24): 12359-12369.
[25] Coley S E, Lavi E, Sawicki S G, et al. Recombinant mouse hepatitis virus strain A59 from cloned, full-length cDNA replicates to high titers in vitro and is fully pathogenic in vivo. J Virol, 2005, 79(5): 3097-3106.
[26] Teke G, Hofmann-Lehmann R, Stallkamp I, et al. Genome organization and reverse genetic analysis of a type I feline coronavirus. J Virol, 2008, 82(4): 1851-1859.
[27] van den Worm S H, Eriksson K K, Zevenhoven J C, et al. Reverse genetics of SARS-related coronavirus using vaccinia virus-based recombination. PLoS ONE, 2012, 7(3): e32857.
[28] Merchlinsky M, Moss B. Introduction of foreign DNA into the vaccinia virus genome by in vitro ligation: recombination-independent selectable cloning vectors. Virology, 1992, 190(1): 522-526.
[29] Carroll M W, Moss B. Poxviruses as expression vectors. Curr Opin Biotechnol, 1997, 8(5): 573-577.
[30] Wathelet M G, Orr M, Frieman M B, et al. Severe acute respiratory syndrome coronavirus evades antiviral signaling: role of nsp1 and rational design of an attenuated strain. J Virol, 2007, 81(21): 11620-11633.
[31] Frieman M, Yount B, Agnihothram S, et al. Molecular determinants of severe acute respiratory syndrome coronavirus pathogenesis and virulence in young and aged mouse models of human disease. J Virol, 2012, 86(2): 884-897.
[32] Pfefferle S, Krähling V, Ditt V, et al. Reverse genetic characterization of the natural genomic deletion in SARS-Coronavirus strain Frankfurt-1 open reading frame 7b reveals an attenuating function of the 7b protein in vitro and in vivo. Virol J, 2009, 6: 131.
[33] Kuo L, Masters PS. The small envelope protein E is not essential for murine coronavirus replication. J Virol, 2003, 77(8): 4597-4608.
[34] Jimenez-Guardeño J M, Nieto-Torres J L, DeDiego M L, et al. The PDZ-binding motif of severe acute respiratory syndrome coronavirus envelope protein is a determinant of viral pathogenesis. PLoS Pathog, 2014, 10(8): e1004320.
[35] Casais R, Dove B, Cavanagh D, et al. Recombinant avian infectious bronchitis virus expressing a heterologous spike gene demonstrates that the spike protein is a determinant of cell tropism. J Virol, 2003, 77(16): 9084-9089.
[36] Bouvet M, Lugari A, Posthuma C C, et al. Coronavirus Nsp10, a critical co-factor for activation of multiple replicative enzymes. J Biol Chem, 2014, 289(37): 25783-25796.
[37] Graham R L, Sims A C, Brockway S M, et al. The nsp2 replicase proteins of murine hepatitis virus and severe acute respiratory syndrome coronavirus are dispensable for viral replication. J Virol, 2005, 79(21): 13399-13411.
[38] Cruz J L, Sola I, Becares M, et al. Coronavirus gene 7 counteracts host defenses and modulates virus virulence. PLoS Pathog, 2011, 7(6): e1002090.
[39] DeDiego M L, Alvarez E, Almazán F, et al. A severe acute respiratory syndrome coronavirus that lacks the E gene is attenuated in vitro and in vivo.J Virol, 2007, 81(4):1701-1713.
[40] Netland J, DeDiego M L, Zhao J, et al. Immunization with an attenuated severe acute respiratory syndrome coronavirus deleted in E protein protects against lethal respiratory disease. Virology, 2010, 399(1): 120-128.
[41] Fett C, DeDiego M L, Regla-Nava J A, et al. Complete protection against severe acute respiratory syndrome coronavirus-mediated lethal respiratory disease in aged mice by immunization with a mouse-adapted virus lacking E protein. J Virol, 2013, 87(12): 6551-6559.
[42] Cavanagh D, Casais R, Armesto M, et al. Manipulation of the infectious bronchitis coronavirus genome for vaccine development and analysis of the accessory proteins. Vaccine, 2007, 25(30): 5558-5562.
[43] Ribes J M, Ortego J, Ceriani J, et al. Transmissible gastroenteritis virus (TGEV)-based vectors with engineered murine tropism express the rotavirus VP7 protein and immunize mice against rotavirus. Virology, 2011, 410(1): 107-118.
[44] Graham R L, Becker M M, Eckerle L D, et al. A live, impaired-fidelity coronavirus vaccine protects in an aged, immunocompromised mouse model of lethal disease. Nat Med, 2012, 18(12): 1820-1826.
[45] Wang J M, Wang L F, Shi Z L. Construction of a non-infectious SARS coronavirus replicon for application in drug screening and analysis of viral protein function. Biochem Biophys Res Commun, 2008, 374(1): 138-142.
[46] Adedeji A O, Singh K, Calcaterra N E, et al. Severe acute respiratory syndrome coronavirus replication inhibitor that interferes with the nucleic acid unwinding of the viral helicase. Antimicrob Agents Chemother, 2012, 56(9): 4718-4728.
[47] Carbajo-Lozoya J, Müller M A, Kallies S, et al. Replication of human coronaviruses SARS-CoV, HCoV-NL63 and HCoV-229E is inhibited by the drug FK506. Virus Res, 2012, 165(1): 112-117.
[48] Kilianski A, Baker S C. Cell-based antiviral screening against coronaviruses: developing virus-specific and broad-spectrum inhibitors. Antiviral Res, 2014, 101: 105-112.
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