新型冠状病毒亚单位疫苗研究进展及现状*
杨依,张晴云,梅坤荣**()
Progress and Current Situation of SARS-CoV-2 Subunit Vaccine Development
YANG Yi,ZHANG Qing-yun,MEI Kun-rong**()

图1. SARS-CoV-2 亚单位疫苗候选抗原的主要类型

Fig.1. Antigen candidates of SARS-CoV-2 subunit vaccine (a) Schematic diagram of the SARS-CoV-2 virion (b) Schematic diagram of S protein trimer in the pre-fusion conformation. TM: Transmembrane region; CT: Cytoplasmic tail (c) Subunit vaccine antigenic design based on S protein (d) Subunit vaccine antigenic design based on RBD (e) Peptide vaccine antigenic design based on specific antigenic epitopes