群体感应系统在合成生物学中的应用*

郑义,郭世英,隋凤翔,杨骐羽,卫雅萱,李晓岩

Applications of Quorum Sensing Systems in Synthetic Biology

Yi ZHENG,Shi-ying GUO,Feng-xiang SUI,Qi-yu YANG,Ya-xuan WEI,Xiao-yan LI

图1 群体感应系统的广义模型[1]

Fig.1 Generalized model of quorum sensing Numbers in the flow charts represent different stages of the QS process. QS signal is synthesised by synthase and spread out of the cell. Those signals couldn’t be transported into cell due to diffusion or active transport until the threshold is reached. QS signals would bind transcription regulators in cell inner,the complex of them could bind QS promotor so that the expression of target gene could be regulated