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Current Status and Prospects of Cellular Immunotherapy Vector Technology |
LIU Xiuying1,LIU Jingjing1,CUI Xinming1,YU Mengyuan1,SHI Yuanyuan1,2,WANG Jianxun1,2,**() |
1 College of Life Sciences, Beijing University of Chinese Medicine, Beijing 100029, China 2 Shenzhen Cell Valley Biopharmaceutical Co., Ltd, Shenzhen 518000, China |
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Abstract In recent years, China’s cellular immunotherapy has developed rapidly, catching up from zero to the international level of excellence. Behind the booming development of cellular immunotherapy, the support of vector technology for gene delivery is indispensable. As a medium for introducing genes into target cells and enabling their expression, vector technology is also one of the major bottlenecks in the development of the industry in terms of how to carry out gene transfer safely and efficiently. By summarizing the current status of the development of vector technology for major applications in the field of cell therapy and comparing the industrialized production process of already marketed products, we hope to provide a reference for the further development of vector technology.
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Received: 15 August 2023
Published: 03 April 2024
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