Orginal Article |
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Advances in Research of Oral Anticancer Drug Nanocarrier |
Xiao-qian PAN1,Xiang-yuan XIONG1,2,**(),Yan-chun GONG2,Zi-ling LI2,Yu-ping LI2 |
1 School of Pharmaceutical Sciences, Jiangxi Science and Technology Normal University,Nanchang 330013,China 2 School of Life Sciences, Jiangxi Science and Technology Normal University,Nanchang 330013,China |
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Abstract Cancer chemotherapy and the patient’s life will be very convenient if oral administration of anti-cancer drugs can be achieved. For most anti-cancer drugs, their bioavailability and treatment efficiency will be decreased by oral administration, due to the gastrointestinal barrier. So it is important to find an effective drug carrier for oral administration of anticancer drugs. The emergence of nanotechnology, led to the development of nano-drugs. Therefor a great breakthrough has been achieved for oral administration of anti-cancer drugs. The research progress of different materials, including synthetic polymer materials, natural macromolecular materials and liposomes as oral anticancer drug carriers, including their in vivo or in vitro studies has been reviewed.
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Received: 22 April 2018
Published: 12 October 2018
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Corresponding Authors:
Xiang-yuan XIONG
E-mail: xyxiong@gmail.com
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