Please wait a minute...

中国生物工程杂志

China Biotechnology
China Biotechnology  2017, Vol. 37 Issue (8): 66-71    DOI: 10.13523/j.cb.20170810
    
Research Progress of Bacterial Lux Bioluminescence Reporter System
CUI Qing-yu, WANG Ming-yu, XU Hai
State Key Laboratory of Microbial Technology, School of Life Sciences, Shandong University, Jinan 250100, China
Download: HTML   PDF(576KB) HTML
Export: BibTeX | EndNote (RIS)      

Abstract  Lux reporter plays an important role in molecular biology, clinical microbiology and biochemical detection, owing to its high sensitivity, fast reaction and convenience. Here the component, types and characteristics of lux reporter system were introduced. Moreover, the recent advance of its application in environment detection, food safety, new drug discovery and tumor locating were reviewed.

Key wordsReporter strains      lux gene      Bioluminescence     
Received: 03 March 2017      Published: 25 August 2017
ZTFLH:  Q819  
Cite this article:

CUI Qing-yu, WANG Ming-yu, XU Hai. Research Progress of Bacterial Lux Bioluminescence Reporter System. China Biotechnology, 2017, 37(8): 66-71.

URL:

https://manu60.magtech.com.cn/biotech/10.13523/j.cb.20170810     OR     https://manu60.magtech.com.cn/biotech/Y2017/V37/I8/66

[1] Smith D C, Douglas A E. The Biology of Symbiosis. London:Edward Arnold, 1987.
[2] 林济民, 王江云. 有趣的发光现象与奇妙的发光蛋白.自然杂志, 2011, 33(5):286-290. Lin J M, Wang J Y. Interesting bioluminescent creatures and amazing fluorescent proteins. Chinese Journal of Nature, 2011, 33(5):286-290.
[3] Hastings J W. Chemistries and colors of bioluminescent reactions:a review. Gene, 1996, 173(1):5-11.
[4] 茆灿泉, 杨树德. 发光细菌lux报告基因系统的评价及应用. 微生物学通报, 2000, 27(4):297-299. Mao C Q, Yang S D. Evaluation and application of lux reporter system in bioluminous bacteria. Microbiology, 2000, 27(4):297-299.
[5] Shah N, Naseby D C. Bioluminescence-based measurement of viability of Pseudomonas aeruginosa ATCC 9027 harbouring plasmid-based lux genes under the control of constitutive promoters. Journal of Applied Microbiology, 2014, 117(5):1373-1387.
[6] Van Dyk T K, Derose E J, Gonye G E. LuxArray, a high-density, genomewide transcription analysis of Escherichia coli using bioluminescent reporter strains. Journal of Bacteriology, 2001,183(19):5496-5505.
[7] Greer L F, Szalay A A. Imaging of light emission from the expression of luciferases in living cells and organisms:a review. Luminescence, 2002,17(1):43-74.
[8] Belas R, Mileham A, Cohn D, et al. Bacterial bioluminescence:isolation and expression of the luciferase genes from Vibrio harveyi. Science, 1982, 218(4574):791-793.
[9] 杜宗军,王祥红,李海峰,等. 发光细菌的研究和应用. 高技术通讯, 2003,13(12):103-106. Du Z J, Wang X H, Li H F,et al. The study and application of luminescent bacteria. Chinese High Technology Letters, 2003,13(12):103-106.
[10] Riendeau D, Meighen E. Co-induction of fatty acid reductase and luciferase during development of bacterial bioluminescence. J Biol Chem, 1980, 255(24):12060-12065.
[11] Meighen E A. Molecular biology of bacterial bioluminescence. Microbiol Rev, 1991,55(1):123-142.
[12] Engebrecht J A, Silverman M. Regulation of expression of bacterial genes for bioluminescence. Genet, 1986, 8(1):31-44.
[13] Glassing A, Lewis T A. An improved Tn7-lux reporter for broad host range, chromosomally-integrated promoter fusions in Gram-negative bacteria. J Microbiol Methods, 2015, 118(11):75-77.
[14] Damron F H, McKenney E S, Barbier M, et al. Construction of mobilizable mini-Tn7 vectors for bioluminescent detection of gram-negative bacteria and single-copy promoter lux reporter analysis. Appl Environ Microbiol, 2013, 79(13):4149-4153.
[15] Bruckbauer S T, Kvitko B H, Karkhoff-Schweizer R R, et al. Tn5/7-lux:a versatile tool for the identification and capture of promoters in gram-negative bacteria. BMC Microbiol, 2015, 15(1):1-16.
[16] Bacconi M, Haag A F, Torre A, et al. A stable luciferase reporter plasmid for in vivo imaging in murine models of Staphylococcus aureus infections. Applied Microbiology and Biotechnology, 100(7):3197-3206.
[17] Francis K P, Joh D, Bellinger-Kawahara C, et al. Monitoring bioluminescent Staphylococcus aureus infections in living mice using a novel luxABCDE construct. Infection and Immunity, 2000,68(6):3594-3600.
[18] Beard S J, Salisbury V, Lewis R J,et al. Expression of lux genes in a clinical isolate of Streptococcus pneumoniae:using bioluminescence to monitor gemifloxacin activity. Antimicrobial Agents and Chemotherapy, 2002,46(2):538-542.
[19] Mesak L R, Yim G, Davies J. Improved lux reporters for use in Staphylococcus aureus. Plasmid,2009,61(3):182-187.
[20] Fischbach M A, Walsh C T. Antibiotics for emerging pathogens. Science, 2009,325(5944):1089-1093.
[21] Projan S J, Youngman P J. Antimicrobials:new solutions badly needed. Current Opinion in Microbiology, 2002,5(5):463-465.
[22] Mesak L R, Qi S, Villanueva I,et al. Staphylococcus aureus promoter-lux reporters for drug discovery. Journal of Antibiotics (Tokyo), 2010,63(8):492-498.
[23] 赵冰,孙赵麟,杨亮,等. 一种利用基因表达变化检测、鉴别抗生素的新方法. 生物工程学报, 2010, 26(1):93-99. Zhao B, Sun Z L, Yang L, et al. Construction of a promoter reporter array for antibiotic screening. Chinese Journal of Biotechnology, 2010, 26(1):93-99.
[24] Fenton M, Casey P G, Hill C, et al. The truncated phage lysin CHAP(k) eliminates Staphylococcus aureus in the nares of mice. Bioengineered Bugs, 2010,1(6):404-407.
[25] Massey S, Johnston K, Mott T M, et al. In vivo bioluminescence imaging of Burkholderia mallei respiratory infection and treatment in the mouse model. Front Microbiol, 2011, 2(4):174-183.
[26] Cronin M, Akin A R, Francis K P. In vivo bioluminescence imaging of intratumoral bacteria. Methods Mol Biol, 2016, 1409(2):69-77.
[27] Leschner S, Weiss S. Noninvasive in vivo imaging to follow bacteria engaged in cancer therapy. Methods Mol Biol, 2016, 1409(2):61-68.
[28] Steinhuber A, Landmann R, Goerke C, et al. Bioluminescence imaging to study the promoter activity of hla of Staphylococcus aureus in vitro and in vivo. International Journal of Medical Microbiology, 2008, 298(7-8):599-605.
[29] Nicholas Lopes, Shawn A Hawkins, Patricia Jegier, et al. Detection of dichloromethane with a bioluminescent (lux) bacterial bioreporter. J Ind Microbiol Biotechnol, 2012, 39(1):45-53.
[30] Prévéral S, Brutesco C, Descamps E C, et al. A bioluminescent arsenite biosensor designed for inline water analyzer. Environ Sci Pollut Res Int, 2017,24(1):25-32..
[31] King J M, Digrazia P M, Applegate B, et al. Rapid, sensitive bioluminescent reporter technology for naphthalene exposure and biodegradation. Science, 1990, 249(4970):778-781..
[32] Heitzer A, Malachowsky K, Thonnard J E. Optical biosensor for environmental on-line monitoring of naphthalene and salicylate bioavailability with an immobilized bioluminescent catabolic reporter bacterium. Appl Environ Microbiol. 1994, 60(5):1487-1494.
[33] Alhadrami H A, Paton G I. The potential applications of SOS-lux biosensors for rapid screening of mutagenic chemicals. FEMS Microbiol Lett. 2013, 344(1):69-76.
[34] Loessner M J, Rudolf M, Scherer S. Evaluation of luciferase reporter bacteriophage A511::luxAB for detection of Listeria monocytogenes in contaminated foods. Appl Environ Microbiol, 1997, 63(8):2961-2965.
[35] Kricka L J. Clinical and biochemical applications of luciferases and luciferins. Anal Biochem, 1988, 175(1):14-21.
No related articles found!